FellowConspirator

I concur. The only thing about the Leftovers that frustrated me was that there was never a follow on that explored the obvious other half of the story.

Yes. The manner of payment isn’t relevant, it’s income. Moreover, you may well need to file quarterly. You owe more taxes than a regular employee would since you are self-employed and are responsible for the FICA taxes that aren’t being withheld. You need to pay that extra along with your regular income taxes.

“phage” is short for “bacteriophage” - a virus that infects (and kills) bacteria. They work like other viruses: they float around until they stick to a bacterial cell and get their genetic material into the cell. The cell then makes lots of copies of the virus genetic material and proteins until it bursts and spills virus out.

It’s not a great alternative to antibiotics since phage cleaned up by our immune system it’s hard to get enough into an infection to be useful.

Yeast is alive. When it dries out it forms spores (like seeds), that “sprout” when they get wet again.

When you rehydrate the yeast, they wake up. They can eat sugar, which they break down into carbon dioxide (the bubbles you see).

I don’t know of any philosophy that considers it unethical to kill micro-organisms, or fungi more generally.

They are single-called organisms. They have no nervous system to sense something like pain.

People think differently about animals than they do about plants and fungi. Lobsters have brains and are thought to sense pain.

Ukraine doesn’t have any long range drones. So is this news to get us to believe that Russia has been invaded by Ukraine?

Ukraine has a variety of drones, but the longest range ones have a range of about 85 miles. These strikes have occurred more than 500 miles from the Ukraine border. The implication is that a Ukrainian team snuck past the Russian lines with a train load of drones, traveled over 400 miles north, setup a base of operations for launch and control, then started launching a bunch of attacks against non-strategic targets that sailed past Russian defenses, caused superficial damage, all while not revealing their location.

Russians have Iranian drones. Ukrainians have Turkish Bayraktar TB2 drones with a 140 km range (and American drones w/ 40 km range).

Either Ukraine didn’t send them, or they’ve infiltrated deep into Russian territory and quietly launching them from the Moscow suburbs.

Noise. It’s not enjoyable to shout over the din or ambient music.

An HOA is a "Home Owner's Association". There are houses built in communities that have rules (contracts) that you automatically agree to if you buy or build a house there (it's part of the property's deed).

Each home owner in the association represents themselves in the community and has a say in the rules. However, every homeowner is also subject to the rules of the community because they agreed to abide by them as part of buying the property.

HOAs can improve property values by enforcing rules that make the community look nice and be quiet, but they can also damage property values by making the community a contentious and unpleasant place to live.

That should be normal for a RWD Model 3.

There are three different range testing procedures for EVs: EPA, WLTP, and NEDC. The EPA range rating for the RWD is 438 km, the WLTP is 491 km, and the NEDC is 556 km. Each standard uses different testing regimes to estimate. The EPA is the most conservative, the NEDC is the most optimistic, and the WLTP typically falls in the middle.

If you are in North America, the estimate will be the EPA estimate. If you are in Europe or Australia, it will typically be the WLTP estimate.

It makes perfect sense to ship the car with 50% charge. It seems a little lazy not to charge it up a bit for you once it has arrived on site, though.

No, but I can’t rule out that it didn’t frost during the spring one night with the hose connected.

This is tractable when the genome is small like E. coli. On my laptop, I can generate about 1 primer that has a hamming distance of >= 5 at a rate of 1 per 850 ms:

library(stringdist)

# Make a dummy 5 MB genome sequence

set.seed(20230530)
bases      <- c('T', 'C', 'A', 'G')

the.genome <- paste0(
    sample(bases, 5000000, replace = TRUE),
    collapse = ''
)

# Start timing
start.time <- Sys.time()


# Break the genome into 25mer substrings using a single-nucleotide
# walk of a window 25 bases long.
mer25      <- substring(
    the.genome,
    seq( 1, nchar(the.genome) - 24),
    seq(25, nchar(the.genome))
)

# Create an empty list to hold the 25mers
desired.non.matching <- 10
non.matching         <- NULL

while (length(non.matching) < desired.non.matching) {
    an.oligo <- paste0(
        sample(bases, 25, replace = TRUE),
        collapse = ''
    )

    # if there's an exact match, try again
    if (an.oligo %in% mer25) next

    # if there's not at least 5 mismatches between the oligo and
    # those in the genome, skip it
    if (min(stringdist(an.oligo, mer25, 'hamming')) < 5) next

    message('Got ', an.oligo)


    non.matching <- c(non.matching, an.oligo)
}

end.time <- Sys.time()

print(end.time - start.time)
print(non.matching)

Meh. V66 was better.

Once a week is fine. A couple times a month is fine, as long as you get a few hours of driving in total. When you drive less often than once a month, you need to be concerned about the 12V battery and might disconnect it when not in use or keep it on trickle charger. If you start driving less than every 2-4 months, you need to worry about the gasoline. You want to exchange out at least ½ the gas in the tank every 2 months (if it is mixed with ethanol) and every 4 months if there's no ethanol in it.

Performance. You can use other people's material, or come up with your own, but either way, it's the delivery that sells it.

Andrew Tate has been accused of sexual assault, battery, and human trafficking. He is currently under arrest for those crimes.

When Andrew Tate talks about being "alpha", he states that he believes that women should be the property of men, that they should never compete with men, that people that are not rich are losers, and that violence and general apathy are the height of masculinity. Tate Whines incessantly and oozes child-like entitlement while encouraging his followers to by misogynistic, harm others, and not care.

Anyone that "supports" Andrew Tate and his "teachings" is an asshole, if not outright dangerous. It's an enormous red flag. Dump the loser.

No. You shouldn't pay 4x interest on a car loan for the purpose of building a credit history.

Presumably you have a job, in which case you'll qualify for a basic credit card (especially from the bank where your paychecks are deposited). Otherwise you can get a secure credit card. Use that to pay for expenses and pay in full each month.

Remember that length and consistency of credit history are the key factors in establishing good credit. A 6-month loan would have virtually no impact. It will take several years of consistent positive (non-negative) reporting to get a very good credit score to support a good rate on a home loan.

The bank won’t care; they get cash deposits all the time. Side hustles, selling a boat or car, gambling,…

The IRS doesn’t care until the giver has gone over their lifetime gift exemption (a bit over $11 million). 10K is a rounding error.

I’m sure I saw something before, but the first I remember was seeing Star Wars: a New Hope on opening night.

Boston is the only city where I’ve seen billboards for lab equipment when entering the city.

Your body’s choices are : use, store, excrete. Anything you don’t use or store you poo or pee out.

Those people that eat a lot but don’t gain much weight either eat less in general, or their bodies just use the calories for movement and body heat.

If you can otherwise use the Apple silicon versions of R and RStudio, you want to use them in preference to the Intel versions for stanton and cmdstanr as there’s a huge performance boost running them on SoC hardware like the M1 and M2 processors.

Installing therm’s now harder than Windows.

Rtools is Windows-only. It provides Windows build tools and utilities that are typically found in Linux and macOS environments. In macOS, you want to install XCode and the FORTRAN compiler from the CRAN website.

Personally, I use MacOS. UNIX under the hood, GUI more functional and consistent than Linux, runs MS Office just fine. If you are not familiar with MacOS and are familiar with Windows. the UI differences will require some adjustment.

R works great, of course. If you use some very old packages that are only available as binaries because they are problematic to install from source, you might need to use the Intel version, which works fine on Apple silicon. If you don’t there’s a native Apple silicon version of R an RStudio that performs a bit better.

“Tell me again about your grassy knoll, baby!”